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Bradykinin B1 R rabbit pAb
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ES7106
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Bradykinin B1 R rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: BDKRB1; BRADYB1; B1 bradykinin receptor; B1R; BK-1 receptor
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human BDKRB1. AA range:201-250
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 40kD
GeneID: 623
Human Swiss-Prot No: P46663
Cellular localization: Cell membrane; Multi-pass membrane protein.
Background: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],