Product name: | KCNQ5 rabbit pAb |
Reactivity: | Human;Mouse |
Alternative Names: | KCNQ5; Potassium voltage-gated channel subfamily KQT member 5; KQT-like 5; Potassium channel subunit alpha KvLQT5; Voltage-gated potassium channel subunit Kv7.5 |
Source: | Rabbit |
Dilutions: | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
Immunogen: | The antiserum was produced against synthesized peptide derived from human KCNQ5. AA range:637-686 |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 100-110kD |
GeneID: | 56479 |
Human Swiss-Prot No: | Q9NR82 |
Cellular localization: | Cell membrane ; Multi-pass membrane protein . |
Background: | This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009], |