PKAβ cat rabbit pAb

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PKAβ cat rabbit pAb

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ES6743

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	PKAβ cat rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	PRKACB; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human KAPCB. AA range:291-340
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	53kD
GeneID:	5567
Human Swiss-Prot No:	P22694
Cellular localization:	Cytoplasm . Cell membrane . Membrane ; Lipid-anchor . Nucleus . Translocates into the nucleus (monomeric catalytic subunit). The inactive holoenzyme is found in the cytoplasm. .
Background:	The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and differentiation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2014],

Western blot analysis of lysates from Jurkat and COLO205 cells, using KAPCB Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human small intestinal carcinoma tissue. 1,primary Antibody was diluted at 1:200(4° overnight). 2, Sodium citrate pH 6.0 was used for antigen retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:2