Sox-6 rabbit pAb

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Sox-6 rabbit pAb

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ES6731

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Sox-6 rabbit pAb
Reactivity:	Human;Mouse;Rat;Monkey
Alternative Names:	SOX6; Transcription factor SOX-6
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human SOX6. AA range:10-59
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	91kD
GeneID:	55553
Human Swiss-Prot No:	P35712
Cellular localization:	Nucleus . Cytoplasm .
Background:	SRY-box 6(SOX6) Homo sapiens This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009],

Western blot analysis of lysates from Jurkat cells, using SOX6 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Tris-EDTA,pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200(4° overnight.3,Secondary antibody was diluted at 1:200(room temperature, 45min).