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TMEM16A rabbit pAb
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ES6706
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50 µL $148.00
100 µL $248.00
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Overview

Product name: TMEM16A rabbit pAb
Reactivity: Human;Mouse;
Alternative Names: ANO1; DOG1; ORAOV2; TAOS2; TMEM16A; Anoctamin-1; Discovered on gastrointestinal stromal tumors protein 1; Oral cancer overexpressed protein 2; Transmembrane protein 16A; Tumor-amplified and overexpressed sequence 2
Source: Rabbit
Dilutions: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human TM16A. AA range:921-970
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 114kD
GeneID: 55107
Human Swiss-Prot No: Q5XXA6
Cellular localization: Cell membrane ; Multi-pass membrane protein . Cytoplasm . Cytoplasmic localization seen in neoplastic cells of head and neck squamous cell carcinoma (HNSCC) tumors. .
Background: domain:The region spanning the fifth and sixth transmembrane domains probably forms the pore-forming region.,function:Acts as a calcium-activated chloride channel. Required for normal tracheal development.,similarity:Belongs to the anoctamin family.,tissue specificity:Broadly expressed with higher levels in liver and skeletal muscle.,