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PMS2/PMS2CL rabbit pAb
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ES6634
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50 µL $148.00
100 µL $248.00
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Overview

Product name: PMS2/PMS2CL rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: PMS2CL; Protein PMS2CL; PMS2-C terminal-like protein; PMS2; PMSL2; Mismatch repair endonuclease PMS2; DNA mismatch repair protein PMS2; PMS1 protein homolog 2
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human PMS2CL. AA range:125-174
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 21kD
GeneID: 5395
Human Swiss-Prot No: Q68D20/P54278
Cellular localization: mismatch repair complex,
Background: caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332). Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Wrong choice of transcript.,similarity:Belongs to the DNA mismatch repair mutL/hexB family.,