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Plasminogen rabbit pAb
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ES6617
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Plasminogen rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: PLG; Plasminogen
Source: Rabbit
Dilutions: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the Internal region of human Plasminogen.
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 90kD
GeneID: 5340
Human Swiss-Prot No: P00747
Cellular localization: Secreted . Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface.
Background: The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009],