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CALML5 rabbit pAb
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ES6569
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50 µL $148.00
100 µL $248.00
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Overview

Product name: CALML5 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: CALML5; CLSP; Calmodulin-like protein 5; Calmodulin-like skin protein
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CALML5. AA range:96-146
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 16kD
GeneID: 51806
Human Swiss-Prot No: Q9NZT1
Cellular localization: extracellular exosome,
Background: This gene encodes a novel calcium binding protein expressed in the epidermis and related to the calmodulin family of calcium binding proteins. Functional studies with recombinant protein demonstrate it does bind calcium and undergoes a conformational change when it does so. Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes. In addition, it can associate with transglutaminase 3, shown to be a key enzyme in the terminal differentiation of keratinocytes. [provided by RefSeq, Jul 2008],