Product name: |
OAT rabbit pAb |
Reactivity: |
Human;Mouse;Rat |
Alternative Names: |
OAT; Ornithine aminotransferase; mitochondrial; Ornithine delta-aminotransferase; Ornithine--oxo-acid aminotransferase |
Source: |
Rabbit |
Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
Immunogen: |
Synthesized peptide derived from OAT . at AA range: 100-180 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
48kD |
GeneID: |
4942 |
Human Swiss-Prot No: |
P04181 |
Cellular localization: |
Mitochondrion matrix . |
Background: |
ornithine aminotransferase(OAT) Homo sapiens This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome. [provided by RefSeq, Jan 2010], |