IκB-β rabbit pAb

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IκB-β rabbit pAb

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ES6385

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	IκB-β rabbit pAb
Reactivity:	Human;Mouse
Alternative Names:	NFKBIB; IKBB; TRIP9; NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300
Immunogen:	The antiserum was produced against synthesized peptide derived from human IkappaB-beta. AA range:4-53
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	37kD
GeneID:	4793
Human Swiss-Prot No:	Q15653
Cellular localization:	Cytoplasm . Nucleus .
Background:	The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011],

Western Blot analysis of NIH-3T3 cells using IκB-β Polyclonal Antibody
Western blot analysis of lysates from NIH/3T3 cells, treated with TNF 20ng/ml 30', using IkappaB-beta Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HT-29 cells using IκB-β antibody.
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).