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MuSK (phospho Tyr755) rabbit pAb
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ES6294
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Overview

Product name: MuSK (phospho Tyr755) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: MUSK; Muscle; skeletal receptor tyrosine-protein kinase; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human MuSK (phospho Tyr755)
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 97kD
GeneID: 4593
Human Swiss-Prot No: O15146
Cellular localization: Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein . Colocalizes with acetylcholine receptors (AChR) to the postsynaptic cell membrane of the neuromuscular junction. .
Background: This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009],