Product name: |
TM4SF1 rabbit pAb |
Reactivity: |
Human;Mouse |
Alternative Names: |
TM4SF1; M3S1; TAAL6; Transmembrane 4 L6 family member 1; Membrane component chromosome 3 surface marker 1; Tumor-associated antigen L6 |
Source: |
Rabbit |
Dilutions: |
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human T4S1. AA range:1-50 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Molecular Weight: |
22kD |
GeneID: |
4071 |
Human Swiss-Prot No: |
P30408 |
Cellular localization: |
Membrane; Multi-pass membrane protein. Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519). . |
Background: |
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008], |