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FAM111B rabbit pAb
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ES5990
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50 µL $148.00
100 µL $248.00
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Overview

Product name: FAM111B rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: FAM111B; CANP; Protein FAM111B; Cancer-associated nucleoprotein
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/200. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human F111B. AA range:281-330
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 85kD
GeneID: 374393
Human Swiss-Prot No: Q6SJ93
Background: This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1. [provided by RefSeq, Apr 2014],