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GROα rabbit pAb
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ES5681
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50 µL $148.00
100 µL $248.00
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Overview

Product name: GROα rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: CXCL1; GRO; GRO1; GROA; MGSA; SCYB1; Growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha(1-73); Melanoma growth stimulatory activity; MGSA; Neutrophil-activating protein 3; NAP-3
Source: Rabbit
Dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GROalpha. AA range:39-88
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Molecular Weight: 11kD
GeneID: 2919
Human Swiss-Prot No: P09341
Cellular localization: Secreted.
Background: This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014],