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SPAK (phospho Ser309) rabbit pAb
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ES5556
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50 µL $148.00
100 µL $248.00
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Overview

Product name: SPAK (phospho Ser309) rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: STK39; SPAK; STE20/SPS1-related proline-alanine-rich protein kinase; Ste-20-related kinase; DCHT; Serine/threonine-protein kinase 39
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human STK39 around the phosphorylation site of Ser311. AA range:277-326
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
GeneID: 27347
Human Swiss-Prot No: Q9UEW8
Cellular localization: Cytoplasm . Nucleus . Nucleus when caspase-cleaved. .
Background: This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008],