VPS26B rabbit pAb

ES4632

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50 µL	$148.00
100 µL	$248.00

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Product name:	VPS26B rabbit pAb
Reactivity:	Human;Mouse
Alternative Names:	VPS26B; Vacuolar protein sorting-associated protein 26B; Vesicle protein sorting 26B
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human VPS26B. AA range:231-280
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	45kD
GeneID:	112936
Human Swiss-Prot No:	Q4G0F5
Cellular localization:	Cytoplasm . Membrane; Peripheral membrane protein . Early endosome . Late endosome . Localizes to early and late endosomal structures (By similarity). .
Background:	function:Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the VPS26 family.,subcellular location:Does not localize to endosomes.,subunit:Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.,