Product name: |
Cdc42EP3 rabbit pAb |
Reactivity: |
Human;Mouse;Rat |
Alternative Names: |
CDC42EP3; BORG2; CEP3; Cdc42 effector protein 3; Binder of Rho GTPases 2; MSE55-related Cdc42-binding protein |
Source: |
Rabbit |
Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. |
Immunogen: |
Synthesized peptide derived from the N-terminal region of human Cdc42EP3. |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
26kD |
GeneID: |
10602 |
Human Swiss-Prot No: |
Q9UKI2 |
Cellular localization: |
Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton . |
Background: |
This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012], |