Vav3 (phospho Tyr173) rabbit pAb

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Vav3 (phospho Tyr173) rabbit pAb

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ES4475

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Vav3 (phospho Tyr173) rabbit pAb
Reactivity:	Human;Mouse
Alternative Names:	VAV3; Guanine nucleotide exchange factor VAV3; VAV-3
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen:	Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173)
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	100kD
GeneID:	10451
Human Swiss-Prot No:	Q9UKW4
Cellular localization:	intracellular,cytosol,plasma membrane,extracellular exosome,
Background:	This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Western Blot analysis of JK cells using Phospho-Vav3 (Y173) Polyclonal Antibody
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).