Product name: | Neuropilin-2 rabbit pAb |
Reactivity: | Human;Mouse;Rat |
Alternative Names: | NRP2; VEGF165R2; Neuropilin-2; Vascular endothelial cell growth factor 165 receptor 2 |
Source: | Rabbit |
Dilutions: | Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human NRP2. AA range:791-840 |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 100kD |
GeneID: | 8828 |
Human Swiss-Prot No: | O60462 |
Cellular localization: | Membrane ; Single-pass type I membrane protein .; [Isoform s9]: Secreted . |
Background: | This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008], |