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Aladin rabbit pAb
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ES3772
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Aladin rabbit pAb
Reactivity: Human;Rat
Alternative Names: AAAS; ADRACALA; GL003; Aladin; Adracalin
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from Aladin . at AA range: 360-440
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 59kD
GeneID: 8086
Human Swiss-Prot No: Q9NRG9
Cellular localization: Nucleus, nuclear pore complex . Cytoplasm, cytoskeleton, spindle pole . Nucleus envelope . In metaphase cells localizes within the spindle with some accumulation around spindle poles, with the highest concentration between the centrosome and metaphase plate (PubMed:26246606). The localization to the spindle is microtubule-mediated (PubMed:26246606). .
Background: The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],