ZAC1 rabbit pAb

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ZAC1 rabbit pAb

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ES3721

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	ZAC1 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	PLAGL1; LOT1; ZAC; Zinc finger protein PLAGL1; Lost on transformation 1; LOT-1; Pleiomorphic adenoma-like protein 1; Tumor supressor ZAC
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human PLAGL1. AA range:311-360
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	50kD
GeneID:	5325
Human Swiss-Prot No:	Q9UM63
Cellular localization:	Nucleus .
Background:	This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues. [provided by RefSeq, Nov 2015],

Western Blot analysis of various cells using ZAC1 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western blot analysis of lysates from 293 cells, using PLAGL1 Antibody. The lane on the right is blocked with the synthesized peptide.
Western blot analysis of the lysates from HeLa cells using PLAGL1 antibody.