Products

XRCC4 rabbit pAb
One-click to copy product information
ES3716
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: XRCC4 rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human XRCC4. AA range:261-310
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 40kD
GeneID: 7518
Human Swiss-Prot No: Q13426
Cellular localization: Nucleus . Chromosome . Localizes to site of double-strand breaks. .; [Protein XRCC4, C-terminus]: Cytoplasm . Translocates from the nucleus to the cytoplasm following cleavage by caspase-3 (CASP3). .
Background: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants. [provided by RefSeq, Dec 2015],