XPA rabbit pAb

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XPA rabbit pAb

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ES3710

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	XPA rabbit pAb
Reactivity:	Human;Mouse
Alternative Names:	XPA; XPAC; DNA repair protein complementing XP-A cells; Xeroderma pigmentosum group A-complementing protein
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human XPA. AA range:211-260
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	40kD
GeneID:	7507
Human Swiss-Prot No:	P23025
Cellular localization:	Nucleus .
Background:	This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009],

Western Blot analysis of various cells using XPA Polyclonal Antibody diluted at 1:500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using XPA Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from COLO205 cells, using XPA Antibody. The lane on the right is blocked with the synthesized peptide.