$148.00/50µL $248.00/100µL
50 µL | $148.00 |
100 µL | $248.00 |
Product name: | TRADD rabbit pAb |
Reactivity: | Human;Mouse;Monkey |
Alternative Names: | TRADD; Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain |
Source: | Rabbit |
Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
Immunogen: | The antiserum was produced against synthesized peptide derived from human TRADD. AA range:251-300 |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 34kD |
GeneID: | 8717 |
Human Swiss-Prot No: | Q15628 |
Cellular localization: | Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Shuttles between the cytoplasm and the nucleus. . |
Background: | The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008], |