SYT rabbit pAb

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SYT rabbit pAb

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ES3544

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	SYT rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	SS18; SSXT; SYT; Protein SSXT; Protein SYT; Synovial sarcoma translocated to X chromosome protein
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human SSXT. AA range:1-50
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	45kD
GeneID:	6760
Human Swiss-Prot No:	Q15532
Cellular localization:	Nucleus .
Background:	disease:A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).,similarity:Belongs to the SS18 family.,tissue specificity:Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.,

Western Blot analysis of various cells using SYT Polyclonal Antibody
Western Blot analysis of COLO205 cells using SYT Polyclonal Antibody
Western blot analysis of lysates from HepG2, Jurkat, and COLO205 cells, using SSXT Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).