Products

STAM2 rabbit pAb
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ES3506
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: STAM2 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: STAM2; HBP; Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human STAM2. AA range:161-210
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 58kD
GeneID: 10254
Human Swiss-Prot No: O75886
Cellular localization: Cytoplasm . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .
Background: The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008],