Products

Scn4b rabbit pAb
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ES3413
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: Scn4b rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: SCN4B; Sodium channel subunit beta-4
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human SCN4B. AA range:61-110
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 27kD
GeneID: 6330
Human Swiss-Prot No: Q8IWT1
Cellular localization: Cell membrane ; Single-pass type I membrane protein .
Background: The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009],