Rho D rabbit pAb

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Rho D rabbit pAb

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ES3350

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Rho D rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	RHOD; ARHD; Rho-related GTP-binding protein RhoD; Rho-related protein HP1; RhoHP1
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen:	The antiserum was produced against synthesized peptide derived from human RHOD. AA range:113-162
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	25kD
GeneID:	29984
Human Swiss-Prot No:	O00212
Cellular localization:	Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome . Colocalizes with RAB5 to early endosomes (By similarity). .
Background:	Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

Western Blot analysis of various cells using Rho D Polyclonal Antibody diluted at 1:500
Western blot analysis of the lysates from HT-29 cells using RHOD antibody.
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).