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Rab 3 GAP p150 rabbit pAb
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ES3289
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Rab 3 GAP p150 rabbit pAb
Reactivity: Human;Mouse;Rat;Monkey
Alternative Names: RAB3GAP2; KIAA0839; Rab3 GTPase-activating protein non-catalytic subunit; RGAP-iso; Rab3 GTPase-activating protein 150 kDa subunit; Rab3-GAP p150; Rab3-GAP150; Rab3-GAP regulatory subunit
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human RAB3GAP2. AA range:417-466
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 156kD
GeneID: 25782
Human Swiss-Prot No: Q9H2M9
Cellular localization: Cytoplasm. In neurons, it is enriched in the synaptic soluble fraction.
Background: The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.[provided by RefSeq, Oct 2009],