The antiserum was produced against synthesized peptide derived from human PRPF18. AA range:182-231
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
40kD
GeneID:
8559
Human Swiss-Prot No:
Q99633
Cellular localization:
Nucleus speckle . Colocalizes with spliceosomal snRNPs. .
Background:
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008],