PMS1 rabbit pAb

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PMS1 rabbit pAb

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ES3240

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	PMS1 rabbit pAb
Reactivity:	Human;Rat;Mouse;
Alternative Names:	PMS1; PMSL1; PMS1 protein homolog 1; DNA mismatch repair protein PMS1
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human PMS1. AA range:441-490
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	105kD
GeneID:	5378
Human Swiss-Prot No:	P54277
Cellular localization:	Nucleus .
Background:	This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using PMS1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western Blot analysis of Jurkat cells using PMS1 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by i
Immunohistochemistry analysis of paraffin-embedded human brain, using PMS1 Antibody. The picture on the right is blocked with the synthesized peptide.