PGE synthase rabbit pAb

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PGE synthase rabbit pAb

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ES3188

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50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	PGE synthase rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	PTGES; MGST1L1; MPGES1; PGES; PIG12; Prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; MGST1-L1; Microsomal prostaglandin E synthase 1; MPGES-1; p53-induced gene 12 protein
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen:	The antiserum was produced against synthesized peptide derived from human PGE synthase. AA range:30-79
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	17kD
GeneID:	9536
Human Swiss-Prot No:	O14684
Cellular localization:	Membrane ; Multi-pass membrane protein . Cytoplasm, perinuclear region . Colocalizes with PTGS1/COX-1 and PTGS2/COX-2 in the perinuclear compartment. .
Background:	prostaglandin E synthase(PTGES) Homo sapiens The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using PGE synthase Polyclonal Antibody diluted at 1:500
Western blot analysis of lysate from A549 cells, using PGE synthase antibody.
Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).