PDZ-RhoGEF rabbit pAb

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PDZ-RhoGEF rabbit pAb

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ES3173

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	PDZ-RhoGEF rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	ARHGEF11; KIAA0380; Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300
Immunogen:	The antiserum was produced against synthesized peptide derived from human ARHGEF11. AA range:198-247
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Molecular Weight:	168kD
GeneID:	9826
Human Swiss-Prot No:	O15085
Cellular localization:	Cytoplasm . Membrane . Translocated to the membrane upon stimulation.
Background:	Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using PDZ-RhoGEF Polyclonal Antibody
Western blot analysis of ARHGEF11 Antibody. The lane on the right is blocked with the ARHGEF11 peptide.
Immunohistochemical analysis of paraffin-embedded human uterus. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).