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Pax-2 rabbit pAb
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ES3152
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Pax-2 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: PAX2; Paired box protein Pax-2
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Pax-2. AA range:144-193
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 42,35kD
GeneID: 5076
Human Swiss-Prot No: Q02962
Cellular localization: Nucleus.
Background: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014],