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NGF rabbit pAb
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ES2958
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50 µL $148.00
100 µL $248.00
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Overview

Product name: NGF rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: NGF; NGFB; Beta-nerve growth factor; Beta-NGF
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human NGF. AA range:33-82
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 27kD
GeneID: 4803
Human Swiss-Prot No: P01138
Cellular localization: Secreted . Endosome lumen . ProNGF is endocytosed after binding to the cell surface receptor formed by SORT1 and NGFR. .
Background: This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008],