| Product name: |
Nectin 3 rabbit pAb |
| Reactivity: |
Human;Mouse |
| Alternative Names: |
PVRL3; PRR3; Poliovirus receptor-related protein 3; CDw113; Nectin-3; CD antigen CD113 |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human PVRL3. AA range:184-233 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
61kD |
| GeneID: |
25945 |
| Human Swiss-Prot No: |
Q9NQS3 |
| Cellular localization: |
Cell membrane ; Single-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane . |
| Background: |
This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011], |
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