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Nectin 3 rabbit pAb
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ES2912
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50 µL $148.00
100 µL $248.00
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Overview

Product name: Nectin 3 rabbit pAb
Reactivity: Human;Mouse
Alternative Names: PVRL3; PRR3; Poliovirus receptor-related protein 3; CDw113; Nectin-3; CD antigen CD113
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human PVRL3. AA range:184-233
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 61kD
GeneID: 25945
Human Swiss-Prot No: Q9NQS3
Cellular localization: Cell membrane ; Single-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane .
Background: This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],