Products

MTHFR rabbit pAb
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ES2863
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: MTHFR rabbit pAb
Reactivity: Human;Mouse;Monkey
Alternative Names: MTHFR; Methylenetetrahydrofolate reductase
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human MTHFR. AA range:314-363
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 75kD
GeneID: 4524
Human Swiss-Prot No: P42898
Cellular localization: cytosol,synapse,
Background: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009],