| Product name: |
MRP-S35 rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
MRPS35; MRPS28; HDCMD11P; MDS023; PSEC0213; 28S ribosomal protein S35; mitochondrial; MRP-S35; S35mt; 28S ribosomal protein S28, mitochondrial; MRP-S28; S28mt |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human MRPS35. AA range:211-260 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
40kD |
| GeneID: |
60488 |
| Human Swiss-Prot No: |
P82673 |
| Cellular localization: |
Mitochondrion . |
| Background: |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has had confusing nomenclature in the literature. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on |
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