Products

Mfn2 rabbit pAb
One-click to copy product information
ES2784
Size： Price：
50 µL $148.00
100 µL $248.00
Manual Send email to us

Overview

Product name: Mfn2 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: MFN2; CPRP1; KIAA0214; Mitofusin-2; Transmembrane GTPase MFN2
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human Mfn2. AA range:354-403
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 86kD
GeneID: 9927
Human Swiss-Prot No: O95140
Cellular localization: Mitochondrion outer membrane ; Multi-pass membrane protein . Colocalizes with BAX during apoptosis. .
Background: This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008],