Products

MerTK rabbit pAb
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ES2779
Size: Price:
50 µL $148.00
100 µL $248.00

Overview

Product name: MerTK rabbit pAb
Reactivity: Human;Rat;Mouse;
Alternative Names: MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK
Source: Rabbit
Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from human MERTK. AA range:10-59
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 110kD
GeneID: 10461
Human Swiss-Prot No: Q12866
Cellular localization: Cell membrane ; Single-pass type I membrane protein .
Background: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008],