Menin rabbit pAb

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Menin rabbit pAb

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ES2778

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	Menin rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	MEN1; SCG2; Menin
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human MEN1. AA range:181-230
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	67kD
GeneID:	4221
Human Swiss-Prot No:	O00255
Cellular localization:	Nucleus . Concentrated in nuclear body-like structures. Relocates to the nuclear matrix upon gamma irradiation.
Background:	This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008],

Western Blot analysis of various cells using Menin Polyclonal Antibody diluted at 1:500
Western Blot analysis of HuvEc cells using Menin Polyclonal Antibody diluted at 1:500
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).