| Product name: |
MEL-1B-R rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
MTNR1B; Melatonin receptor type 1B; Mel-1B-R; Mel1b receptor |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human MTR1B. AA range:301-350 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
40kD |
| GeneID: |
4544 |
| Human Swiss-Prot No: |
P49286 |
| Cellular localization: |
Cell membrane; Multi-pass membrane protein. |
| Background: |
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008], |
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