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mAChR M4 rabbit pAb
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ES2737
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50 µL $148.00
100 µL $248.00
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Overview

Product name: mAChR M4 rabbit pAb
Reactivity: Human;Mouse;Rat
Alternative Names: CHRM4; Muscarinic acetylcholine receptor M4
Source: Rabbit
Dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CHRM4. AA range:236-285
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 53kD
GeneID: 1132
Human Swiss-Prot No: P08173
Cellular localization: Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, mouse studies link its function to adenylyl cyclase inhibition. [provided by RefSeq, Jul 2008],