$148.00/50µL $248.00/100µL
50 µL | $148.00 |
100 µL | $248.00 |
Product name: | Lfc rabbit pAb |
Reactivity: | Human;Mouse;Rat |
Alternative Names: | ARHGEF2; KIAA0651; LFP40; Rho guanine nucleotide exchange factor 2; Guanine nucleotide exchange factor H1; GEF-H1; Microtubule-regulated Rho-GEF; Proliferating cell nucleolar antigen p40 |
Source: | Rabbit |
Dilutions: | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
Immunogen: | The antiserum was produced against synthesized peptide derived from C-ternal human ARHGEF2. AA range:851-900 |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 111kD |
GeneID: | 9181 |
Human Swiss-Prot No: | Q92974 |
Cellular localization: | Cytoplasm, cytoskeleton . Cytoplasm . Cell junction, tight junction . Golgi apparatus . Cytoplasm, cytoskeleton, spindle . Cell projection, ruffle membrane . Cytoplasmic vesicle . Localizes to the tips of cortical microtubules of the mitotic spindle during cell division, and is further released upon microtubule depolymerization (PubMed:15827085). Recruited into membrane ruffles induced by S.flexneri at tight junctions of polarized epithelial cells (PubMed:19043560). Colocalized with NOD2 and RIPK2 in vesicles and with the cytoskeleton (PubMed:21887730). . |
Background: | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009], |