$148.00/50µL $248.00/100µL
50 µL | $148.00 |
100 µL | $248.00 |
Product name: | KIF4A rabbit pAb |
Reactivity: | Human;Rat;Mouse; |
Alternative Names: | KIF4A; KIF4; Chromosome-associated kinesin KIF4A; Chromokinesin-A |
Source: | Rabbit |
Dilutions: | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
Immunogen: | The antiserum was produced against synthesized peptide derived from human KIF4A. AA range:1171-1220 |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 140kD |
GeneID: | 24137 |
Human Swiss-Prot No: | O95239 |
Cellular localization: | Nucleus matrix . Cytoplasm . Cytoplasm, cytoskeleton, spindle . Midbody . Chromosome . Associates with chromosomes at all stage of mitosis (PubMed:11736643, PubMed:15297875, PubMed:15625105). Chromatin localization is dependent on iron-sulfur cluster binding (PubMed:29848660). In anaphase, associates with the mitotic spindle midzone (PubMed:15297875). In telophase and cytokinesis, co-localizes with CIAO2B at the spindle midzone and midbody (PubMed:29848660, PubMed:15297875). Co-localizes with PRC1 in early mitosis and at the spindle midzone from anaphase B to telophase (PubMed:15297875, PubMed:15625105). Does not localize to the nucleolus (PubMed:11736643). . |
Background: | kinesin family member 4A(KIF4A) Homo sapiens This gene encodes a member of the kinesin 4 subfamily of kinesin related proteins. The encoded protein is an ATP dependent microtubule-based motor protein that is involved in the intracellular transport of membranous organelles. This protein also associates with condensed chromosome arms and may be involved in maintaining chromosome integrity during mitosis. This protein may also be involved in the organization of the central spindle prior to cytokinesis. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, Mar 2010], |