| Product name: |
IRAK-1 rabbit pAb |
| Reactivity: |
Human;Mouse;Rat |
| Alternative Names: |
IRAK1; IRAK; Interleukin-1 receptor-associated kinase 1; IRAK-1 |
| Source: |
Rabbit |
| Dilutions: |
WB 1:500-2000;IHC-p 1:50-300 |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human IRAK1. AA range:353-402 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
76kD |
| GeneID: |
3654 |
| Human Swiss-Prot No: |
P51617 |
| Cellular localization: |
Cytoplasm . Nucleus . Lipid droplet . Translocates to the nucleus when sumoylated. RSAD2/viperin recruits it to the lipid droplet (By similarity). . |
| Background: |
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
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