IQGAP1 rabbit pAb

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IQGAP1 rabbit pAb

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ES2639

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	IQGAP1 rabbit pAb
Reactivity:	Human;Mouse
Alternative Names:	IQGAP1; KIAA0051; Ras GTPase-activating-like protein IQGAP1; p195
Source:	Rabbit
Dilutions:	WB 1:500-2000;IHC-p 1:50-300
Immunogen:	The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	190kD
GeneID:	8826
Human Swiss-Prot No:	P46940
Cellular localization:	Cell membrane . Nucleus . Cytoplasm . Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816). .
Background:	IQ motif containing GTPase activating protein 1(IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],

Western Blot analysis of various cells using IQGAP1 Polyclonal Antibody diluted at 1:1000
Western Blot analysis of HeLa cells using IQGAP1 Polyclonal Antibody diluted at 1:1000
Western blot analysis of the lysates from K562 cells using IQGAP1 antibody.
Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).