E2F-6 rabbit pAb

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E2F-6 rabbit pAb

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ES2214

Size：	Price：
50 µL	$148.00
100 µL	$248.00

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Overview

Product name:	E2F-6 rabbit pAb
Reactivity:	Human;Mouse;Rat
Alternative Names:	E2F6; Transcription factor E2F6; E2F-6
Source:	Rabbit
Dilutions:	Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen:	The antiserum was produced against synthesized peptide derived from human E2F6. AA range:141-190
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	31kD
GeneID:	1876
Human Swiss-Prot No:	O75461
Cellular localization:	Nucleus .
Background:	This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

Western Blot analysis of various cells using E2F-6 Polyclonal Antibody diluted at 1:500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Western Blot analysis of HepG2 cells using E2F-6 Polyclonal Antibody diluted at 1:500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using E2F6 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HepG2 cells, using E2F6 Antibody. The lane on the right is blocked with the synthesized peptide.