Product name: | Desmin rabbit pAb |
Reactivity: | Human;Mouse;Rat |
Alternative Names: | DES; Desmin |
Source: | Rabbit |
Dilutions: | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Immunogen: | The antiserum was produced against synthesized peptide derived from human Desmin. AA range:26-75 |
Storage: | -20°C/1 year |
Clonality: | Polyclonal |
Isotype: | IgG |
Concentration: | 1 mg/ml |
Observed Band: | 54kD |
GeneID: | 1674 |
Human Swiss-Prot No: | P17661 |
Cellular localization: | Cytoplasmic |
Background: | This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008], |