Product name: |
Cyclophilin F rabbit pAb |
Reactivity: |
Human;Mouse;Rat |
Alternative Names: |
PPIF; CYP3; Peptidyl-prolyl cis-trans isomerase F; mitochondrial; PPIase F; Cyclophilin F; Rotamase F |
Source: |
Rabbit |
Dilutions: |
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from human PPIF. AA range:86-135 |
Storage: |
-20°C/1 year |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1 mg/ml |
Observed Band: |
22kD |
GeneID: |
10105 |
Human Swiss-Prot No: |
P30405 |
Cellular localization: |
Mitochondrion matrix . |
Background: |
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008], |